A multimodal brain imaging dataset on sleep deprivation in young and old humans: The Sleepy Brain Project I
The Stockholm Sleepy Brain Study I is a functional brain imaging study where 48 younger (20-30 years) and 36 older (65-75 years) healthy participants underwent magnetic resonance imaging after normal sleep and partial sleep deprivation in a crossover design. We performed three experiments investigating emotional mimicry, empathy for pain, and cognitive reappraisal, as well as resting state functional magnetic resonance imaging (fMRI). We also acquired T1- and T2-weighted structural images and diffusion tensor images. On the night before imaging, participants were monitored with ambulatory polysomnography and were instructed to sleep either as usual or only three hours. Participants came to the scanner the following evening. Besides MRI scanning, participants underwent behavioral tests and contributed blood samples, which have been stored in a biobank and used for DNA analyses. Participants also completed a variety of self-report measures. The resulting multimodal dataset may be useful for hypothesis generation or independent validation of effects of sleep deprivation and aging, as well as investigation of cross-sectional associations between our different outcomes.
The faces and arrows task-based fMRI experiment data will be published at a later time.
Raw polysomnography data are available upon request.
The currently published data set includes:
Hands task-based fMRI data
Resting state fMRI data
Demographics, surveys, questionnaire data
Eye tracking data
High resolution T1-weighted and T2-weighted structural scans
B0 field map data
Diffusion-weighted imaging scans
DNA analysis results
Data Descriptor Manuscript
A preprint of the corresponding data descriptor manuscript (submitted) is available at the Karolinska Institutet open archive.
- Gustav Nilsonne
- Sandra Tamm
- Paolo d’Onofrio
- Hanna Å Thuné
- Johanna Schwarz
- Torbjörn Åkerstedt
- Catharina Lavebratt
- Jia Jia Liu
- Kristoffer NT Månsson
- Tina Sundelin
- John Axelsson
- Predrag Petrovic
- Peter Fransson
- Göran Kecklund
- Håkan Fischer
- Mats Lekander
Contact Information:Name: Gustav Nilsonne
Acknowledgements and Funding:
We are grateful to Diana Cortes and Roberta Nagai for assistance with polysomnography recordings, to Birgitta Mannerstedt Fogelfors for assistance with screening, instructions to participants, and blood sampling, to Rouslan Sitnikov and Jonathan Berrebi for assistance with MRI sequences and auxiliary equipment, and to Hannes Ingre for entering sleep diary data into a spreadsheet.
External Publication Links:Intrinsic brain connectivity after partial sleep deprivation in young and older adults: results from the Stockholm Sleepy Brain study
The effect of sleep restriction on empathy for pain: An fMRI study in younger and older adults
Effects of late-night short-sleep on in-home polysomnography: relation to adult age and sex
GE Discovery 3T
How to cite this dataset:
In addition to any citation requirements in the dataset summary please use the following to cite this dataset:
This data was obtained from the OpenfMRI database. Its accession number is ds000201
Direct Links to data:
Revision: 1.0.5 Date Set: Dec. 2, 2017, 3:02 a.m.
- Rearranged data in the zip archive
Revision: 1.0.4 Date Set: Oct. 9, 2017, 1:41 a.m.
- Added resting state data and hands task data
- Fixed dataset_description.json and task-PVT_beh.json formatting issues
- In participants.tsv, replaced empty cells and 'NA' with 'n/a'
- Replaced participants_codebook.tsv with participants.json
- Moved extra particpant data to a separate file in sourcedata
- Renamed sessions.tsv files to comply with BIDS
- Updated README
- Updated and renamed task-workingmemorytest.json
Revision: 1.0.3 Date Set: Oct. 17, 2016, 4:36 p.m.
- Added a note to README mentioning that polysomnography data is available upon request
from the submitter
Revision: 1.0.2 Date Set: Oct. 13, 2016, 10:21 p.m.
- Removed polysomnography recording data for all subjects. This was requested by the submitter.
Revision: 1.0.1 Date Set: Sept. 10, 2016, 1:55 a.m.
- Updated participants.tsv with more fields
- Added PVT data
Revision: 1.0.0 Date Set: May 19, 2016, 9:10 p.m.
- Initial publishing